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Image Search Results
Journal: Cell & Bioscience
Article Title: NOTCH2NLC GGC repeat expansions cause retinal neurodegeneration in neuronal intranuclear inclusion disease mouse model
doi: 10.1186/s13578-026-01542-x
Figure Lengend Snippet: Expression of NOTCH2NLC-polyG in the retina of NIID mice. A – F Co-immunostaining on retinas of NIID and control mice using anti-Flag (indicating NOTCH2NLC-polyG) with anti-VSX2 ( A ), anti-PAX6 ( B ), anti-RBPMS ( C ), anti-Rhodopsin ( D ), anti-Arrestin C ( E ), or anti-RPE65 ( F ). Red: VSX2 ( A ), PAX6 ( B ), RBPMS ( C ), Rhodopsin ( D ), Arrestin C ( E ) or RPE65 ( F ); Green: NOTCH2NLC-polyG; Blue: DAPI. Scale bar = 50 μm. The yellow dashed box indicates the region shown at higher magnification. G The percentage of cells co-expressing PolyG and VSX2, PAX6 or RBPMS. H The quantification of the number of VSX2-, PAX6-, and RBPMS-positive cells in NIID and control mice. Data are presented as mean ± SEM. N = 6 per group, ** P = 0.0012 (PAX6), ** P = 0.0021 (RBPMS), ns = no significance, two-tailed t-test. I Transmission electron microscopy images of intranuclear inclusions in the INL and RGC layer of the retinas of NIID mice. The yellow dashed box indicates the region shown at higher magnification. The yellow arrows indicate the round-shaped, filamentous, non-membranous intranuclear inclusions. Scale bar = 1 μm
Article Snippet: Primary antibodies used in this study include: RBPMS (Thermo Fisher Scientific, PA5-31231, 1/300),
Techniques: Expressing, Immunostaining, Control, Two Tailed Test, Transmission Assay, Electron Microscopy
Journal: Frontiers in Immunology
Article Title: Regional Dichotomy in Enteric Mucosal Immune Responses to a Persistent Mycobacterium avium ssp. paratuberculosis Infection
doi: 10.3389/fimmu.2020.01020
Figure Lengend Snippet: Zero-order protein-protein interaction network of differentially expressed genes comparing MAP-infected DPP to PBS control intestinal segments. Data was drawn using NetworkAnalyst . Red, upregulated; green, downregulated. Node size reflects the number of protein-protein interactions, with larger nodes representing a greater number of annotated interactions.
Article Snippet:
Techniques: Infection, Control, Protein-Protein interactions